Newer Anticoagulants Can Be Used Off-Label
نویسندگان
چکیده
منابع مشابه
Newer anticoagulants can be used off-label.
hat is the diagnosis? Stroke neurologists make use of inductive reasoning, a probabilistic exercise, to determine stroke mechanism. Where ≥1 possible mechanism exists, we typically adopt the philosophy of Occam's razor, assuming that 1 mechanism is dominant. The ensuing approach to preventive treatment rationally follows the determination of stroke mechanism. The appearance of an embolic-lookin...
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e are presented here with a sketchy story of a presumed recent stroke onset that is embolic-looking while taking aspirin and clopidogrel for a coronary stent that had been inserted some 6 months earlier. Presumably, imaging consisting of computed tomography or magnetic resonance had shown large artery infarcts in differing arterial territories and of varying ages. Whether earlier infarcts had o...
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Warfarin is very effective in preventing stroke in patients with atrial fibrillation. However, its use is limited due to fear of hemorrhagic complications, unpredictable anticoagulant effects related to multiple drug interactions and dietary restrictions, a narrow therapeutic window, frequent difficulty maintaining the anticoagulant effect within a narrow therapeutic window, and the need for in...
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With a growing number of new anticoagulant/antiplatelet agents being developed, it is likely that an increasing number of patients taking these drugs will present for surgery and other procedures. A familiarity with mechanisms of action and drug interactions helps to maintain optimal patient safety in the perioperative period. Furthermore, it is crucial for anesthesiologists to remain current o...
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Non-valvular atrial fibrillation is a recognized risk factor for stroke and systemic embolism. It has been clearly established that warfarin reduces the risk of stroke and systemic embolism in persons with atrial fibrillation and additional risk factors for stroke. The use of warfarin, however, requires frequent monitoring, and there is great variability in patient response to warfarin. Warfari...
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ژورنال
عنوان ژورنال: Stroke
سال: 2014
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.113.002694